Dr. Tadahiro Makise, the esteemed director of our clinic, has spent over 30 years traveling to more than 85 countries in pursuit of natural substances that enhance health. His journey culminated in the establishment of his clinic in Osaka, Japan.

Dr. Makise has extensively treated patients suffering from chronic skin conditions such as psoriasis, atopic dermatitis, and prurigo nodularis　(nodular prurigo), which are often resistant to conventional treatments. Many of these patients have benefited from unique lotions and ointments developed and manufactured in our clinic in Osaka and our laboratory in Okinawa Japan, effectively addressing various skin issues. We are proud to offer products with unmatched reliability, crafted from years of clinical experience and supported by numerous users and patients.