Rooted in Japanese Wisdom.
Refined by Science.
From Japan, MAKISE LAB brings together traditional botanicals, thoughtful processing, medical perspective, and relationships built across borders.
Our Story
A brand shaped by curiosity and connection.
MAKISE LAB grew from a long-standing interest in how traditional knowledge, natural materials, and modern research can inform everyday wellness.
Its origins are closely connected to Dr. Tadahiro Makise, a Japanese physician whose work has taken him across approximately 90 countries. Through conversations with physicians, researchers, manufacturers, and people from many cultures, one principle became clear: meaningful ideas often begin with listening carefully and connecting the right people.
Today, MAKISE LAB is operated by GODPRODUCT CO., LTD. in Osaka, Japan. We continue to develop and select products with respect for their origins, attention to how they are made, and a commitment to communicating responsibly.
Our Approach
Respect the source. Examine the evidence. Formulate with purpose.
Our work is guided by three complementary perspectives.
Japanese wisdom
We study botanicals and food materials with meaningful cultural histories, respecting the context in which they have been used.
Scientific perspective
We consider available research, ingredient characteristics, and processing methods without making claims beyond the evidence.
Thoughtful daily use
We value clear formulations, practical routines, and products designed to be understood and continued with confidence.

Medical Perspective
A physician's lifelong inquiry.
Dr. Tadahiro Makise
Physician | Author | Medical Advisor
Dr. Makise has spent more than 25 years exploring healthy aging through clinical practice, international exchange, and the study of natural materials. His travels across approximately 90 countries have brought him into contact with diverse medical traditions and approaches to wellness.
His role at MAKISE LAB is to bring a careful medical perspective to ingredient selection and product direction - asking what is known, what remains uncertain, and how information can be communicated responsibly.
"Respect tradition, examine the evidence, and create something people can understand and continue."

From Japan
Materials with a story. Methods with intention.
Our interest extends beyond an ingredient's name. We look at where it comes from, how it has been used, how it is processed, and whether the finished form is appropriate for modern daily life.
Manufactured in Japan
Carefully made.
Closely managed.
MAKISE LAB supplements are manufactured in Japan by our trusted production partner, ASTRIM CO., LTD., at a health-food GMP-certified facility.
From raw-material receipt through manufacturing, inspection, and shipment, each stage is managed under established quality and hygiene procedures. ASTRIM also operates HACCP-based controls and maintains managed clean zones throughout its manufacturing and packaging processes.

Human connection opens the way to new possibilities.People | Knowledge | Technology | Borders
Human Connection
Ideas become possible when the right people meet.
GODPRODUCT's work has always begun with relationships. Across medicine, research, manufacturing, product development, technology, and international business, we connect people and organizations whose knowledge can complement one another.
Rather than being limited by one field or one country, we listen to the purpose of each project and consider what combination of experience and expertise can move it forward.
This international network - and the trust built through it - continues to shape MAKISE LAB.
Our Values
What guides every decision.
Respect before reinvention
We value the history and cultural context of a material before considering its place in a modern formula.
Clarity over exaggeration
We aim to communicate what a product is - and what it is not - with care, transparency, and restraint.
Quality with purpose
Ingredients, processing, format, and daily usability are considered together rather than in isolation.
Relationships built to last
We work through trusted partnerships in Japan and internationally, valuing continuity as much as innovation.
Company Information
MAKISE LAB,
Japan.
Japanese botanical wellness, developed through trusted relationships and guided by medical perspective.
- Brand
- MAKISE LAB
- Operated by
- GODPRODUCT CO., LTD.
- Medical Partner
- MAKISE CLINIC
- Location
- 1-7-14 Imabashi, Chuo-ku, Osaka 541-0042, Japan
- Website
- godproduct.jp
- Contact
- Contact MAKISE LAB
Continue Exploring
Discover thoughtful wellness from Japan.
Explore the MAKISE LAB collection or contact us to learn more about our approach.