Rooted in Japanese tradition
We begin with botanicals and food materials that have a meaningful place in Japanese culture.
MAKISE LIFEUP LAB · JAPAN
Japanese Botanical
Wellness
Nature Grown. Science Refined.
Japanese botanicals, precise processing, and medical insight—brought together for a considered daily wellness routine.
Explore the CollectionAll products are shipped directly from Japan.
A Japanese Botanical Perspective
Meet Alpinia zerumbet.
Known in Japan as getto, Shell Ginger has long been part of daily life in Okinawa.
MAKISE LAB studies this distinctive botanical and applies carefully selected Japanese processing methods to preserve its natural character. It is the foundation of our JIPANG Ginger collection.
Not common ginger. Not turmeric.
A distinctive member of the ginger family.
A distinctive member of the ginger family.
Our Approach
Tradition × Processing × Medical Insight
A focused approach to Japanese wellness—respecting natural materials while examining how they can fit modern daily life.
Refined through precise processing
Thoughtful production methods help retain the qualities that make each selected material distinctive.
Guided by medical insight
Dr. Tadahiro Makise’s clinical perspective informs our careful, purpose-driven approach to formulation.
The Collection
Daily wellness,
made with intention.
A concise collection of Japanese supplements selected for ingredient quality, practical daily use, and thoughtful formulation.
JIPANG Ginger Collection
JIPANG Ginger OPTIMAL
Shell Ginger with selected polyphenol-rich ingredients and Japanese seaweed-derived ascophyllan.
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JIPANG Ginger WASABI
Shell Ginger paired with Japanese wasabi and gotu kola in a focused botanical formula.
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JIPANG Ginger Powder
Pure Shell Ginger leaf powder with naturally occurring dietary fiber, made for simple everyday use.
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Japanese Perilla Seed Oil
EGOMA OIL
Cold-pressed Japanese perilla seed oil, portioned into convenient sachets for daily use.
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Doctor-Supervised Supplement
Doctors Mega Lactoferrin
An enteric-coated lactoferrin supplement designed as part of a considered daily wellness routine.
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Japanese Proteoglycan
PROTEOL GⅡ
Salmon nasal cartilage-derived proteoglycan, formulated for everyday joint and connective-tissue wellness.
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Japanese Daily Wellness
SLIMDALE
A Japanese daily wellness formula combining green tea-derived catechins with plant-derived Lactobacillus K-1.
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Selected Japanese Botanicals
Three distinctive botanicals,
thoughtfully selected.
Okinawa BotanicalShell Ginger
Japanese BotanicalJapanese Wasabi
Japanese Food TraditionPerilla Seed
Medical Guidance
A physician’s perspective on everyday wellness.
Dr. Tadahiro Makise
Physician · Author · Medical Advisor
For more than 25 years, Dr. Makise has explored healthy aging through clinical practice, international research, and the careful study of natural materials. His perspective guides the MAKISE LIFEUP LAB approach: respect tradition, examine the evidence, and formulate with purpose.
“The best daily wellness practice is one that can be understood, trusted, and continued.”
Botanical Notes
A modern Japanese
botanical journal.
Inspired by the Japanese tradition of observing and understanding natural materials, MAKISE LAB explores botanicals, ingredients, processing, and the thinking behind each formula.
Shell Ginger Notes
From Okinawan tradition to botanical research.
Meet Alpinia zerumbet, known in Japan as getto—a botanical with a distinctive place in Okinawan life.
Read the introduction
Processing Notes
Why low-temperature, reduced-pressure processing?
A closer look at the carefully controlled Japanese method selected for our Shell Ginger leaf powder.
Read the introductionWasabi Notes
Why authentic Japanese wasabi?
More than its familiar heat—a look at why genuine Japanese wasabi was selected for the JIPANG Ginger formula.
Read the introductionFrom Japan to Your Door
Made in Japan.
Shipped from Japan.
Our products are fulfilled directly from Japan. Product availability, shipping charges, and any applicable destination requirements are shown during purchase.
MAKISE LIFEUP LAB is the international home of MAKISE LAB, Japan.
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.